An aqueous antifungal composition comprising from about 10 to about 30 percent by weight of ethyl alcohol, from about 2 to about 5 percent by weight of benzyl alcohol and the remainder to 100 percent water, and a system of use of the article for destroying or diminishing the number of microbes on a surface contaminated therewith.
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(a) Field of the Invention
The invention relates to aqueous ethanolic antimicrobial compositions for treating surfaces in order to render them essentially free of dangerous microbial contamination or lessen the degree of harmful parasitic contamination thereon.
(b) Information Disclosure Statement
It is well-known the ethyl alcohol, in conjunction with water, in concentrations of 50-90percent provides broad spectrum germicidal activity. Aqueous ethyl alcohol (70%) is known to be virucidal against lipophilic and a few hydrophilic viruses.Hard surface disinfectant compositions based on aqueous ethyl alcohol are also known. For instance, a present commercially available hard surface disinfectant product based on ethyl alcohol contains as active ingredients 79 percent ethyl alcohol and 0.1percent o-phenylphenol, minor amounts of inert ingredients, and the equilibrium water. This product, when applied to environmental surfaces, kills staph and strep germs, athlete’s foot fungus, hydrophilic viruses such as rhino-39, and lipophilic viruses such asinfluenza A2 (Japan), influenza type B, herpes simplex 1, adeno type 2 and vaccinia.
Benzyl alcohol is known to possess antibacterial and antifungal actions. Furthermore, U.S. Pat. No. 4,200,655 discloses that benzyl alcohol possesses virucidal activity when tested against three strains of human rhinovirus, herpes simplexvirus types 2 and 1 and two strains of influenza virus in suspension at concentrations in the assortment of from 1.5 to 6% and this compositions containing benzyl alcohol as active component are intended for topical virucidal use both in vivo and in vitro,particularly for use on both palms and particularly for preventing transmission of rhinoviruses.
Chemical Abstracts 66: 44357p (1967) discloses the inhibitory effect of benzyl alcohol on the multiplication of SV-40, vaccinia and herpes simplex viruses in concentrations of 9-14 mM.
No. 4,446,153 reveals a skin sanitizing composition particularly suited as a teat dip or udder wash for milk cows comprising at least one phenyl alkanol such as benzyl alcohol because the microbicidal or sanitizing ingredient. Aqueouscompositions comprising 1 and 4% benzyl alcohol are exemplified.
No. 4,695,453 discloses thickened alcoholic antibacterial compositions containing one or more alcohols having antibacterial action and that the compositions preferably include ethanol, propanol and benzyl alcohol because the activeingredients. The preferred compositions preferably contain a major portion (between about 40 and about 50% by weight) of ethanol that comprises 4% water, a minor portion (between about 20% and 30 percent by weight) of anhydrous isopropanol, and a nominalamount (about 0.5% to about 2% by weight) of benzyl alcohol. This patent refers to some commercial antibacterial product named Spitacid.RTM. Accessible from Henkel containing approximately 46 percent by weight ethanol (containing about 4% water), 27% anhydrousisopropanol, 1 percent benzyl alcohol and the balance water.
German Offenlegungsschrift No. 3,117,792 discloses virucidal compositions for disinfecting skin, hands, surfaces and instruments comprising aqueous solutions containing 3 to 55% by weight of mono- or polyhydroxy aliphatic alcohols with up to8 carbon atoms in the aliphatic chain, 0.1 to 5% by weight of phenol or substituted phenols and two to 40 percent by weight of an anionic, cationic, nonionic or amphoteric surfactant. A makeup is illustrated which comprises 78.0% ethanol, 2.0% benzylalcohol, 2.5% 4-chloro-2-benzylphenol, 0.15% 2-hydroxytrichlorodiphenyl ether, 6.0% benzalkonium chloride, 3.0% alkylamine oxide as well as the balance cologne and water.
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